Publications

  1. Sun J, Sepulveda JL, Komissarova EV, Hills C, Seckar TD, Del Portillo A, Narine M LeFevre, Hayk Simonyan, Colin Young, Gloria Su, Wang TC, Sepulveda AR. CDKN2A-p16 deletion and activated KRASG12D drive Barrett’s-like gland hyperplasia-metaplasia and synergize in the development of dysplasia pre-cancer lesions. Cell and Molecular Gastroenterology and Hepatology 2024; 17 (5): 769-784. PMID: 38296052.
  2. Bartley AN, Mills AM, Konnick E, Overman M, Ventura CB, Souter L, Colasacco C, Stadler ZK, Kerr S, Howitt B, Hampel H, Adams SF, Johnson W, Magi-Galluzzi C, Sepulveda AR, Broaddus RR. Mismatch repair and microsatellite instability testing for immune checkpoint inhibitor therapy: guideline from the College of American Pathologists in collaboration with the Association for Molecular Pathology and Fight Colorectal Cancer.  Arch Pathol Lab Med 2022 Oct 1;146(10):1194-1210. PMID: 35920830.
  3. Abrams JA, Del Portillo A, Hills C, Compres G, Friedman RA, Cheng B, Poneros J, Lightdale CJ, de la Rue R, di Pietro M, Fitzgerald RC, Sepulveda A, Wang TC. Randomized Controlled Trial of the Gastrin/CCK2 Receptor Antagonist Netazepide in Patients with Barrett’s Esophagus. Cancer Prev Res (Phila). 2021 Jun; 14(6):675-682. PMID: 33782049
  4. Lee M, Kudose S, Del Portillo A, Ko HM, Lee H, Pittman ME, Salomao MA, Sepulveda AR, Lagana SM. Invasive carcinoma versus pseudoinvasion: interobserver variability in the assessment of left-sided colorectal polypectomies. J Clin Pathol. 2021 Apr 12: jclinpath-2021-207406. Doi: 10.1136/jclinpath-2021-207406. Online ahead of print.PMID: 33846218
  5. Kunze B, Wein F, Fang HY, Anand A, Baumeister T, Strangmann J, Gerland S, Ingermann J, Münch NS, Wiethaler M, Sahm V, Sastre AH, Lange S, Lightdale CJ, Bokhari A, Falk GW, Friedman RA, Ginsberg GG, Iyer PG, Jin Z, Nakagawa H, Shawber CJ, Nguyen T, Raab WJ, Dalerba P, Rustgi AK, Sepulveda AR, Wang KK, Schmid RM, Wang TC, Abrams JA, Quante M. Notch Signaling Mediates Differentiation in Barrett’s Esophagus and Promotes Progression to Adenocarcinoma. Gastroenterology. 2020 Apr 20:S0016-5085(20)30516-3. Doi: 10.1053/j.gastro.2020.04.033. Online ahead of print. PMID: 32325086
  6. Li Y, Zhang X, Zhu S, Dejene EA, Peng W, Sepulveda A, Seto E.Li Y, et al. HDAC10 Regulates Cancer Stem-Like Cell Properties in KRAS-Driven Lung Adenocarcinoma. Cancer Res. 2020 Aug 15;80(16):3265-3278. PMID: 32540961
  7. Chang W, Wang H, Kim W, Liu Y, Deng H, Liu H, Jiang Z, Niu Z, Sheng W, Nápoles OC, Sun Y, Xu J, Sepulveda A, Hayakawa Y, Bass AJ, Wang TC. Hormonal Suppression of Stem Cells Inhibits Symmetric Cell Division and Gastric Tumorigenesis. Cell Stem Cell. 2020 May 7;26(5):739-754.e8. doi: 10.1016/j.stem.2020.01.020. Epub 2020 Mar 5. PMID: 32142681
  8. Sheng W, Malagola E, Nienhüser H, Zhang Z, Kim W, Zamechek L, Sepulveda A, Hata M, Hayakawa Y, Zhao CM, Chen D, Wang TC.Sheng W, et al. Hypergastrinemia Expands Gastric ECL Cells Through CCK2R+ Progenitor Cells via ERK Activation.  Cell Mol Gastroenterol Hepatol. 2020;10(2):434-449.e1. doi: 10.1016/j.jcmgh.2020.04.008. April. PMID: 32330731
  9. Jorge L Sepulveda, Elena V Komissarova, Sarawut Kongkarnka, Richard Friedman, Jon M Davison, Brynn Levy, Diana Bryk, Vaidehi Jobanputra, Armando Del Portillo, Gary https://pubmed.ncbi.nlm.nih.gov/31001805/W Falk, Charles J Lightdale, Julian A Abrams, Timothy C Wang, Antonia R Sepulveda* High-Resolution Genomic Alterations in Barrett’s Metaplasia of Patients Who Progress to Esophageal Dysplasia and Adenocarcinoma. Int J Cancer, 2019, Nov 15;145(10):2754-2766. PMID: 31001805.
  10. Del Portillo A, Komissarova EV, Bokhari A, Hills, C, de Gonzalez AK, Kongkarnaka, S, Remotti HE, Sepulveda JL, and Sepulveda AR*. Downregulation of Friend Leukemia Integration 1 (FLI1) Follows the Stepwise Progression to Gastric Adenocarcinoma. 2019, Oncotarget. 10(39):3852-3864. PMID: 31231464.
  11. Fazlollahi L, Remotti HE, Iuga A, Yang HM, Lagana SM, Sepulveda AR*. HER2 Heterogeneity in Gastroesophageal Cancer Detected by Testing Biopsy and Resection Specimens. Arch Pathol Lab Med. 2018 Apr;142(4):516-522. PMID: 28782986